Humans have been using mind-altering substances, or hallucinogens, for a very long time. The origin of hallucinogens has been discovered about 2,500 years ago in the Caribbean region, and traditional cultures from America to Africa use hallucinogenic substances for spiritual purposes. When used for religious purposes, these substances are often used in conjunction with other substances such as tobacco. The phenomenon of hallucinations is an Abnormal Perception of the individual in which he is conscious and awake but without the stimulus of a real sensory receptor beyond himself. Hallucinations, in other words, perception without a clear object. Hallucinations are usually found in drug users and drug users. Ibogaine; The drug is derived from the iboga plant from Africa, ibogaine is a hallucinogenic drug with a long history of tribal rituals. More recently, the drug has shown an opportunity to be used to treat addictions in the Mexican and European regions, where the use of ibogaine drugs is not prohibited for treatment purposes or is called ibogaine treatment.

The use of ibogaine as a therapy can cause heart rhythm and vomiting disorders as a common side effect. The Multidisciplinary Association for Psychedelic Research (MAPS) reported that an estimated 1 in 300 ibogaine users abandoned this drug. The group studied the long-term effects of ibogaine on treatment program patients through ibogaine in New Zealand and Mexico.